More large-scale research is needed to confirm this. For example, a study found that a high-monocyte-to-low-lymphocyte ratio can help identify disease activity in people with ulcerative colitis. Treatment of elevated monocytes depends on the cause. Your doctor may have to do more tests to determine the underlying cause. Generally, treatment may include the following:. When it comes to white blood cells, you want to keep them all within the healthy range.
Regular exercise is an important component to overall good health and maintaining the right blood counts. Since monocytes respond to inflammation, an anti-inflammatory diet might be beneficial. Anti-inflammatory foods include:. The Mediterranean diet is a good example of an anti-inflammatory diet. It includes a lot of fresh vegetables, fruit, nuts, seeds, fish, olive oil, and whole grains. The white blood cell count is complicated. If you think your monocyte level is too high, talk to your doctor about why that is, whether you need treatment, and if lifestyle changes may be helpful.
Monocytes, along with other types of white blood cells, are a vital part of your immune system. They help protect you against infection and illness. If your monocytes are higher than they should be, your doctor will work with you to find the cause and start any treatments that may be necessary. Manage Your Award. Grants Management Contacts. Prior Approvals. Annual Reporting and Auditing. Transfer of a Grant. Grant Closeout. Cancer Training at NCI.
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List of Partners vendors. Monocytes are a type of white blood cell. Monocytes are formed in the bone marrow and are released into peripheral blood, where they circulate for several days. Monocytes are probably best known for their role in serving as something akin to reserve forces in the military. Some of them may be called up if needed, to form the precursors of two other types of white blood cells: tissue macrophages and dendritic cells.
But monocytes also have other roles in infection and disease, some of which have nothing to do with tissue macrophages and dendritic cells. Until recently, the main role of monocytes was considered to be sensing the environment and replenishing the pool of tissue macrophages and dendritic cells, as needed. Now it is known that subsets of monocytes have distinct markers or protein tags on the outside, and these subsets may also behave differently. Three kinds of human monocytes are now described.
The remaining 20 percent can be classified by their protein tags as non-classical monocytes and intermediate monocytes. When it comes to the different kinds of monocytes and how they function in the immune system, researchers are still working out the details, and much more is currently known about mouse monocytes than human monocytes.
It is not yet certain in humans, however, what proportion of monocytes are mobile enough to go in and out of tissues, and evidence suggests there may be kinds of monocytes that can engulf and digest, or phagocytize, invaders but without actively promoting inflammation.
A good number of human monocytes are believed to migrate into tissues throughout your body where they may reside or give rise to macrophages that perform essential functions to fight infection and clean up dead cells. Many of the types that do not cause tuberculosis called nontuberculous mycobacteria Some types of HPV cause skin warts, and other types cause genital warts growths in or around the vagina, penis, or rectum.
Infection with some HPV People are also at risk of developing some types of leukemia Overview of Leukemia Leukemias are cancers of white blood cells or of cells that develop into white blood cells.
White blood cells develop from stem cells in the bone marrow. Sometimes the development goes awry Symptoms vary depending on the specific microorganism that causes the infection but often involve the lungs or skin. Antibiotics are given to treat infections, and a stem cell transplant Stem Cell Transplantation Stem cell transplantation is the removal of stem cells undifferentiated cells from a healthy person and their injection into someone who has a serious blood disorder.
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